Posts Tagged ‘ DES ’

Top 10 Drug Legal News Topics For 2012

December 24th, 2012. By AbiK

LawyersandSettlements.com recently shared its list of the hottest consumer-related pharmaceutical legal news stories during the last year. Of note is that while the top drug-related topic on the legal news website in 2011 had been Tylenol—prompted by concerns over a series of Tylenol recall notices as reported by The New York Times; for 2012, the most sought out pharmaceutical topics have shifted to women’s health.

Third-generation contraceptives such as Yasmin/Yaz, NuvaRing and Mirena top the list this year as numerous birth control lawsuits either settled, or began the process of consolidation into multi-district litigation (MDL).

Reader interest in Yaz/Yasmin rose in response to Yasmin lawsuit settlements that were announced in April (In re Yasmin and Yaz (Drospirenone) Marketing, Sales Practices and Product Liability Litigation, 09-md-02100, U.S. District Court, Southern District of Illinois, East St. Louis). Bloomberg reported Bayer AG settled about 500 Yasmin lawsuits over claims of blood clots that had, in some cases, led to stroke or heart attack.

Along with Yaz, readers remained concerned about NuvaRing (etonogestrel/ethinyl estradiol) and blood clot risk even as a new study on non-oral hormonal contraception, published in the British Medical Journal (BMJ 2012;344:e2990), was presented at the annual meeting of the American College of Obstetricians and Gynecologists (May, 2012). The study, aimed at quantifying NuvaRing blood clot risk, indicated no significant difference in risk of venous thromboembolism when compared to oral contraceptives.

Still, NuvaRing lawsuits continue and have been consolidated into a federal MDL court in Missouri (In re: NuvaRing Products Liability Litigation, No. 08-md-1964, JPML, Eastern District Missouri). As of September 5, 2012, according to the U.S. Panel on Multidistrict Litigation, more than 1,000 NuvaRing lawsuits have been filed.

Mirena IUD (levonorgestrel) saw an increase in reader interest after August 2012, as Bayer Healthcare Pharmaceuticals, Inc. submitted an Application for Centralized Management of Certain Cases involving Mirena. As FoxNews reported (11/11/12), the request seeks to create a multi-district litigation (MDL) for 16 pending Mirena lawsuits in NJ that allege Mirena caused uterine perforation, infection and hemorrhaging injuries.

After the top three women’s health-related drugs, Pradaxa (dabigatran), an alternative to warfarin, joined the list this year making the Top 5. In November 2012, the FDA issued a Drug Safety Communication regarding Pradaxa bleeding events which in turn helped drive reader interest.

Thousands of LawyersandSettlements.com monthly readers have followed the latest legal news and information on these topics, many of which have fallen from the radar of traditional media outlets.

“We believe these issues are of great importance to the public, mostly due to the life-changing impact they can have on an individual,” said Stephen King, CEO. “Some of our most interesting stories of the year related to pharmaceuticals. Many of them have pending lawsuits or have had substantial settlements related to their life-altering side effects and it’s important to get this information out to the public. While many pharmaceutical companies continue to earn significant profits, people are suffering. They may think they have no recourse but in many cases they do. By keeping these topics alive, LawyersandSettlements.com is helping people stay up-to-date on these important topics every day.”

The LawyersandSettlements.com Top 10 Pharmaceutical Topics of 2012, along with the potential side effects readers were seeking information on, are:

1. Yasmin/YAZ (gall bladder disease, blood clots, deep vein thrombosis, pulmonary embolism)

2. NuvaRing & Mirena (blood clots, infection, perforation of the uterus)

3. Pradaxa (uncontrollable bleeding, lack of an available antidote)

4. Granuflo (elevated bicarbonate levels, risk for metabolic alkalosis)

5. SSRIs (birth defects including heart defects, spina bifida, cleft palate, club foot, PPHN)

6. Actos (bladder cancer, heart failure, kidney failure, rhabdomyolysis)

7. Diethylstilbestrol/DES (cancer)

8. Crestor / Statins (diabetes, cardiomyopathy, rhabdomyolysis)

9. Fosamax (bone fractures, esophageal cancer)

10. Propecia (sexual dysfunction, erectile dysfunction, sterility, prostate cancer)

LawyersandSettlements.com readers are looking for the latest and most comprehensive legal news available. Those seeking legal help can request assistance by completing a form which is then distributed to attorneys specializing in these cases. Over two and a half million people visit the site yearly, and hundreds of thousands of request forms have been submitted by qualified readers looking for legal guidance.

Tags: Actos, Birth Control Side Effects, Class Action Lawsuit, Crestor, DES, Drug Injury, Drug Lawsuit, Fosamax, Granuflo, Lawsuit, Legal News, Mirena, NuvaRing, Pradaxa, Propecia, SSRI, statins, Yasmin, Yaz
Posted in Class Action, Drugs/Medical, Emerging Issues | No Comments »

Concerned about DES Exposure? Take this DES Self-Assessment

August 20th, 2012. By AbiK

Pregnancy drug DES has been back in the media spotlight lately as more and more women become aware of possible DES exposure they may have experienced in utero. DES—or diethylstilbestrol—was prescribed to pregnant women during between the 1940s and the early 1970s to help prevent miscarriage.

DES was ultimately removed from the market when studies revealed the drug’s link to certain cancers, among other potential side effects. DES risks include vaginal and cervical cancers for women whose mothers had taken diethylstilbestrol during pregnancy. Additionally, harmful DES side effects may include breast cancer, early menopause and infertility in women who had actually taken the drug.

The Centers for Disease Control and Prevention (CDC) has a DES Consumer Guide that provides information about DES. The web page includes a DES Self-Assessment Guide that helps indicate whether an individual has had the potential to have been exposed to DES and the possible DES health risks if, indeed, DES exposure did occur. Please note: the DES Self-Assessment Guide cannot specifically determine whether a person was actually exposed to DES, but it does provide a guide for further discussion with a healthcare professional.

If you’re a DES daughter or think you may have been exposed to DES in utero and have experienced harmful side effects, you may also want to consider your legal options. DES victims can fill out a complaint form for a DES attorney to review here.

Tags: Breast Cancer, Cervical Cancer, DES, DES Daughters, DES Mothers, Diethylstilbestrol, Pregnancy Drug, Vaginal Cancer
Posted in Drugs/Medical, Emerging Issues, lawsuits | 1 Comment »

You’ve Heard of Thalidomide Babies, what about DES Babies?

February 21st, 2012. By AbiK

 

It’s a startling reality that DES Mothers, DES Daughters and DES Sons live with—that not many people know about or have heard about the pregnancy drug DES—diethylstilbestrol—or the harmful effects its had on both mothers who took the drug, and children who were exposed to the drug in utero.

DES was prescribed during the 1940’s to the 1970’s to expectant mothers who were at risk for miscarriage or pre-term delivery. The drug, however, was found to potentially cause clear cell adenocarcinoma (CCA), a rare form of vaginal and cervical cancer; reproductive tract structural changes such as a T-shaped uterus; complications in pregnancy such as ectopic (tubal) pregnancy and pre-term delivery; and infertility.

DES finally had its FDA approval revoked in 2000 (it had been recommended that doctors not prescibe it in 1971)—but not until potentially millions of mothers and children had been negatively affected by it. And those children are now between forty and seventy years of age or so—some of whom have lived through infertility or miscarriages of their own with out knowing that the reason could be connected to exposure to DES.

And that begs the question: why do so few people know about DES and the damage its caused? DES seems to be in the shadows of thalidomide—so much so that it’s been referred to as the ‘silent thalidomide’ in the press.

There are some possible reasons why, of course.

First, thalidomide was never approved for use in the US. DES was approved which perhaps made it appear less pernicious—after all, ‘my doctor prescribed it’.

Second, thalidomide babies could not help but evoke the collective sympathy and outrage of all who had seen a picture of an innocent newborn with severe birth defects such as missing or shortened arms or other severe disfigurement. There are no alarming pictures of DES victims—only faces; and those faces look just like you or me.

And finally, thalidomide, by its horrific nature, wove its way into popular culture—probably the most familiar evidence of this for many is the Billy Joel lyric from “We Didn’t Start the Fire”.

Diethylstilbestrol (DES), however, has potentially affected many more women in the US—and their children and perhaps their children’s children (aptly called ‘DES Third Generation’)—than thalidomide and is in some ways a much more heinous drug in that DES is the one that slipped through the proverbial cracks—the one that the FDA didn’t put the brakes on—soon enough.

Perhaps you now know about DES. But more importantly, do you know if you were on DES or exposed to it?

 

Tags: DES, DES Babies, DES Daughters, DES Lawsuit, Diethylstilbestrol, Pregnancy Drug, Stilboestrol, Thalidomide, Thalidomide Babies
Posted in Drugs/Medical, Emerging Issues, lawsuits, Personal Injury | 25 Comments »