These days, there are many drugs to keep track of. It’s not just the brand name drug anymore; patients could be taking a generic equivalent. So, this week, Pleading Ignorance looks at the SSRIs and SNRIs to give you the brand name, manufacturer, generic version and the generic’s manufacturer. Consider it your one-stop cheat sheet on some of the more commonly prescribed antidepressants.
Brand name |
Ingredient |
Made By |
Generic |
Made By |
|
|
|
|
|
Celexa (SSRI) |
citalopram hydrobromide |
Forest Laboratories |
citalopram |
Eon Labs, Inc., Aurobindo Pharma Limited, Purepac Pharmaceutical Co., Dr. Reddy’s Laboratories Limited, Corepharma LLC |
Lexapro (SSRI) |
escitalopram oxalate |
Forest Laboratories |
escitalopram |
Alphrapharm |
Paxil/Seroxat (SSRI) |
paroxetine hydrochloride |
GlaxoSmithKline |
paroxetine |
Apotex, Alphapharm, Teva, Aurobindo Pharma, Zydus Pharms USA, Caraco |
Prozac (SSRI) |
fluoxetine hydrochloride |
Eli Lilly and Company |
fluoxetine |
ESI Lederle (tentative approval) |
Symbyax (SSRI) |
olanzapine and fluoxetine hydrochloride |
Eli Lilly and Company |
olanzapine/ fluoxetine |
Teva Pharms (tentative approval, July 17, 2007) |
Zoloft (SSRI) |
sertraline hydrochloride |
Pfizer Pharmaceuticals |
sertraline |
Dr Reddy’s Labs Ltd, Teva, Genpharm, Aurobindo Pharma, Sandoz and many others |
Zyprexa (atypical antipsychotic) |
olanzapine |
Eli Lilly and Company |
olanzapine |
All tentative approval: Dr. Reddy’s Labs Inc, Teva Pharms, Mylan PHarma, Sandoz, Barr Pharms, Roxane |
Cymbalta (SNRI) |
duloxetine hydrochloride |
Eli Lilly and Company |
duloxetine |
No generic so far as I can tell |
Effexor (SNRI) |
venlafaxine |
Wyeth |
venlafaxine hydrochloride |
Aurobindo, Mylan, Teva, Dr Reddy’s Labs Ltd, Caraco and others |
The information in the chart above was found at either drugs@fda, or on the individual drug manufacturer’s website. As far as I can tell, this information is correct as of the date it was written—and it is not intended to replace the information you might receive from your doctor or medical practitioner (hey, have to say it, we’re a legal site). Talk to your doctor or pharmicist for medical advice.
C’mon. You know you’ve seen that Pristiq ad once or twice—the one with that little wind-up doll (yes, the one with the circa-1970’s get-up that would drive any of us into a state of mild depression)—and you’ve thought to yourself, “Gee, I’ve had days when I kind of felt that way”. Admit it folks, you’ve been there—maybe not in mauve polyester, but you’ve been there.
Now, you may or may not have taken that thought to the next level: the “I need help” level. Most of us don’t. But if you have, you’ve most likely “talked to your doctor” as only “he can determine whether [fill in anti-depressant drug name here] is right for you”.
And if you’ve left your doctor’s office with a little slip of paper to be dropped off at the pharmacy, you may have been prescribed an SSRI, SNRI, NDRI or MAOI. Perhaps you’re feeling high as a kite on the hopes that you’ll be giddier than a glee club as soon as you get that scrip filled. But, take pause. For while you fantasize about your future mental state, do you really know what you’ve just been given?
What follows is a mini primer to the world of anti-depressants—and, as this is a legal news site, the links provided will lead you to information on safety concerns and some of the resulting litigation that’s gone on.
There are actually many different types of antidepressants. Not just the brand names, but the actual types of drugs themselves that work on different chemicals in the brain. Generally, antidepressants aim to reverse depressive symptoms and stabilize mood by increasing the amounts of certain chemicals that are found in the brain. The type of antidepressant depends on the chemicals being affected.
Although there is no one answer to the question, “What causes depression?” scientists believe that chemicals in the brain play a role in some forms of depression. The brain has several hundred types of chemical messengers—also called neurotransmitters—that send messages between brain cells. Of these, three neurotransmitters specifically are targeted by the various antidepressants, to different degrees.
Serotonin is thought to play a role in controlling anxiety, mood, sleep, sexuality and appetite.
Norepinephrine is thought to play a role in sleep and alertness and is also thought to play Read the rest of this entry »
Nearly every year, researchers on drug company payrolls publish some ridiculous study with claims that more people may be dying from suicide due to a black box warning about an increased risk of suicide in young people on the labels of SSRI and SNRI antidepressants as a ruse to increase sales of drugs.
Judging from a new study out this month, with a June 2, 2009 headline on WebMD stating: “Are Antidepressant Warnings Causing Harm?”, apparently this year is no exception even though in the US there were 164.2 million prescriptions dispensed for antidepressants in 2008, compared to 143 million in 2004, according to IMS Health, a healthcare information company.
The study, published in the Archives of General Psychiatry, claims there has been a drastic drop in the diagnosis of depression in adults and kids.
Although the adverse effects of women taking psychiatric drugs while pregnant related to birth defects and infant withdrawal syndrome are often discussed or reported, the serious adverse effects on the sex lives and reproductive systems of millions of young couples are rarely mentioned.
Whatever the reason, due to the ever widening marketing campaigns by the psycho-pharmaceutical industry, young people need to be warned before they get conned into taking psychiatric drugs. Read the rest of this entry »
This week, journalist Philip Dawdy reported on the popular website Furious Seasons that Wyeth’s Effexor me-too drug Pristiq, FDA approved in early 2008, had already generated 1,272 adverse event reports in the FDA’s MedWatch system through the end of 2008, and wrote with live links to the reports:
“It’s discouraging that 17 of those reports involve completed suicides through the end of 2008. There are also 48 reports of suicidal ideation through the end of 2008.”
“That’s a lot in such a short period of time, especially considering that this drug isn’t exactly widely used,” Dawdy points out. Read the rest of this entry »