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Symptoms of Gadolinium Toxicity?

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Seattle, WAMany people who have undergone a MRI with gadolinium contrast agent, who may not have kidney or renal problems, are nevertheless concerned that their symptoms of joint pain, muscle weakness and skin problems could lead to Nephrogenic Systemic Fibrosis (NSF), also known as Nephrogenic fibrosing dermopathy (NFD)— a preventable but potentially fatal illness.

MRIThese symptoms-- certain skin thickening, joint problems, rashes, skin disorders, bone pain, joint pain and joint stiffening—are all signs of NSF/NFD, originally known as a Scleromyxoedema-like cutaneous disease in patients with renal disease. But many people who do not have kidney or renal problems are understandably worried.

Stephen says he had numerous MRIs, all with gadolinium injections. "I have pain in my chest, kidney area, stiffness of the joints in my arms, legs and ankles," he says. "As well, there is a distinct odor and discoloration of my urine ever since the first gadolinium injection. I also experience frequent outbreaks of a rash on my hands."

Diane also says she has complications from just one gadolinium contrast injection. "Since the injection I have elevated liver function, a burning feeling, pain walking and a multitude of symptoms I have never had before," she says. "The doctors deny that it was caused by the injection even though I have never had any health problems before. I have had numerous tests, and no other factors have been found to have caused this. The doctors ordered the contrast [agent] when it was not needed, and now that I have these symptoms they refuse to help."

And this complaint from Darren, who says he was given gadolinium without knowledge of any "deadly" side affects. "Since last April, 2008 I have experienced rashes (there are dark marks on my arms from them) and burning of certain organs, and now I have joint swelling in my knees along with hip pain," he says. "It seems like I have arthritis because when I sit down it hurts to bend down or get up."

Lastly, from Susan: "All my joints hurt and my feet feel like they are on fire," she says. "They hurt all night and when I get up in the morning I can hardly walk with so much pain. If I stop and sit down for a while then try to walk…my feet are very stiff and my ankles and part of my legs are filled with pain." Susan says she has had similar problems for many years but nothing like this new pain, and the right side of her back close to her kidney hurts. She had several MRIs after back surgery and the last MRI was 4 years ago—when these new pains began.

In healthy patients, Gadolinium toxicity is kept to a minimum because the kidneys are able to flush out the Gadolinium contrast agents. However, in patients with kidney or renal problems, the Gadolinium contrast agents stay in the body longer, exposing the patient to Gadolinium toxicity and increasing the risk of NSF/NFD.

If you or a loved one has experienced any skin problems, joint pain and muscle weakness with or without kidney or renal problems after undergoing a MRI with gadolinium contrast agent you may want to seek legal help. MRI Gadolinium side effect lawsuits have been filed against contrast agents Magnevist, MultiHance, Omniscan, OptiMARK and ProHance.

READ ABOUT GADOLINIUM LAWSUITS

Gadolinium Legal Help

If you have suffered losses in this case, please send your complaint to a lawyer who will review your possible [Gadolinium Lawsuit] at no cost or obligation.

READER COMMENTS

Posted by

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Yesterday, I had an MRI with contrast to view a cyst on my kidney. My urin has since had a very medicinal/antiseptic oder. I have chronic kidney disease. Is this a normal smell or should I be concerned? I do not remember this happening in the past.

Posted by

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I went to local hospital for ivp test with contrast dye at radiology dept for possiale kidney stones tec tried to install pig tail to install the contrast dye first tube was installed tec asked if I felt any resalts of dye I said no then other tec shows up and said install second tube of dye my right started to swell badly and pain felt like a steam roller rolling over at this time no I have majior health issues to my side of my body head to toe for real this dye is toxic my opion think twice I am 51 years old and on social security unable to work due to neglagent hospital staff because they missed vein with pigtail still installed dye not only once but twice then sent me home with majior swelling and pain calling it a staff infection story goes on thanks valorie n

Posted by

on
I too have the same symptoms. My kidneys hurt. When I bent I out of
breathe. My back shoots pain to
my chest and both Rib cage. I had lots of MRIs with contrast. When the awful pain started I had two cat scan, Xrays and stress test, nothing was found. The pain is getting worse. I need HELP! I believe it's the contrast dye

Posted by

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I wonder if this can cause stomach issues. I've had several studies with contrast & since then I've been having issue after issue with no findings from the doctors.

Posted by

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hours after mri/mra with and without contrast I have had legs aches, burning, in hips and both legs. Ankles burning as well. Done feb 28th 2018 at west valley imaging. I cant walk right anymore and suffer every day, I did a 24 hour urine test a month later and GAD level was off the charts. I was told by drs that this did not cause any of this. It is safe and no reactions to legs are heard of. PLEASE HELP ME. I feel I cant go on. I kNOW they the injection which was so they say dotaram caused this and been to 5 dr already in a month. NO ONE has a clue. I was healthy till they injected me which I asked and asked it safe and they all said it has risks but these risks and symptoms I have they said are NOT related. I have records of everything. Please help.

Posted by

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I've had Gadolinium contrast injections (Gadavist), I've been experiencing muscle pain, tingling in extremities, burning sensation also, really disappointed of doctors, and even more when they caused the problem, hope something is done about this, because it just ruined my life, being bedridden all day.

Is there a way to remove this from my body?

Posted by

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About 7 years ago I received gadolinium before an MRI. That same month my fingernails started to be affected. Ever since then I have been troubled with very unsightly nails, i.e. splitting, a growth that I scrape off and practically no nails to trim because of length.

Posted by

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I just had two MRIs two days apart. Both used gadolinium contrast material. While I didn't experience any pain or other significant issues, I did have an usual event which occurred about 12 hours after each gadolinium MRI. While asleep at night, I awoke from repeated sneezing and a severely runny nose. I thought I had caught cold at the radiology site so I took a cold tablet which helped with the symptoms and they disappeared by the following morning. Two days later, which was yesterday, I had another gadolinium MRI and last night the same sneezy thing happened. I've taken another cold tablet this morning and I feel OK.

I haven't been able to find this particular side effect in the literature but I'm sure it was caused by the gadolinium. Has anyone else experienced this flu-like syndrome from gad?

Posted by

on
I have only 1 kidney and had numerous Breast MRIs yearly fo about 7 years. For a couple of years I had difficulty swallowing. After my last MRI I have not been able to kneel at all and used to do yoga. Normally extremely active and healthy but recently pain in arms knees hips etc. how do I know if it is related to the MRI GADOLINIUM? I don't want another MRI ever I want to get back to my normal self! When will it go away? I perfectly healthy before!

Posted by

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Hello there. I have no kidney function problems, and two days ago I had an MRI with a gadolinium contrast. Tonight, I am in such pain, that I literally don't know where to put myself. About an hour after I had my MRI, I noticed a slight pain in my groin. I put it down to perhaps pulling a muscle when running (not very fast!) to catch my train to the hospital that morning. Over the last 24 hours or so, the pain, all on my left side, has intensified...groin, lower back, outer hip and down to my knee. I can't get down the stairs, and am hobbling around in such pain, it is making me cry. Even remaining still does not help. I live in the UK. The out of hours medical advice people will be calling me in a few hours time to evaluate again. After reading all the comments here, I am not feeling very positive of the outcome. But...after reading about gadolinium poisoning, at least I now have more information than I did a few hours ago.

Posted by

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I had 3 ct scans with contrast and an MRI all within a 3 month period. I have no existing kidney issues. After all of the tests days after i would develop terrible flank pain. My doctor agrees with me that it is the contrast. My GFR was much lower than it normally is every time I have this test. However they will not put it in my medical record that this is an issue. I am afraid to have it again as the pain is just terrible.

Is this causing long term damage to my kidneys and why 5 days after the test are my kidneys still trying to get rid of this stuff?

Posted by

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I had an MRI back in April of 2014 that took about an hour and a half. During that time I began to experience a sharp pain in my right hip. I thought it would soon pass but by August of the same year, there were more server pain in my left shoulder and arm.
Also, I've notice swelling between my thighs and front right hip. Often why trying to sleep there's a sharp pain in my right leg and sometimes all over my entire body. When exercising there was a feeling that my legs were not moving properly. At times I feel very week and stiff. So I'm wondering........

Posted by

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There is a test to determine the current level of Gadolinium in your system- might be helpful when trying to give yourself a month over month, or yearly comparison point. Called a Gadolinium 24 hour urine test run by Mayo Clinic Laboratories (basically send in your urine- we worked through a local regional clinic).

Spouse had mri w/ contrast (magnevist), had similar symptoms as noted above - light sensitivity (had to wear sunglasses at night), greater facial numbness, aching/pressure in ribs, blood pressure fluctuating randomly/rapidly, heart palpitations, aching in arm, joint pains in various places, etc. After noting there was a similar taste on tongue weeks later as was experienced during the time of injection- spouse determined to have a physical to test kidney functionality, and had the mentioned Gadolinium test. Took the test about 3 weeks after MRI. Kidneys are fine, Gadolinium came back at 5.6 (I believe the measuring unit is mcg), where a normal range is below .4 ... way high for a substance supposed to come out within 2-24 hours.

Originally spouse had MRI done checking for cause of numbness occurring in various parts of body and 3 herniated discs in neck were discovered (suspect due to sports/chiropractic injury), brain looked fine. After MRI there was a heavy increase in facial numbness, Orthopaedic doc and a Neurosurgeon wanted to wait on fixing neck and just give it time to heal on its own- but referred to other specialists due to symptoms experienced post MRI. At this point spouse has seen the following post- MRI:
Cardiologist- for heart /blood pressure issues being experienced post MRI
Orthopedic- for neck recommendations
Neurosurgeon- in case eye issues/facial numbness were caused by brain (at Ortho's recommendation)
Neurologist- at Neurosurgeons recommendation
Ophthalmologist (x2)- for vision
Nephrologist/Renal- at Cardiologist recommendation (to discuss how to remove toxin from blood)

At this point: heart, kidney's, brain- everything looks/tests fine. Except Gadolinium levels...

Posted by

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What should I do at this point of severe pain, after having Brain MRI with a contrast named Dotarem 3 weeks ago? The drug was approved by FDA in 2013.

Posted by

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I had a contrast brain MRI done three days ago, for the first time. I decided to share my experience - as the same evening after the procedure I started having weird symptoms that I have never experienced before - and that was also the first time I started to search what this procedure is about and what is the substance I was injected with (hospital staff didnt give me any information and I somehow felt its a safe procedure, they must know what they are doing). The symptoms that developed in about 8 hours: numb hand (the injected one), heavy arms and legs, stiffness, pressure at the back of my head, problems concentrating.. Symptoms that developed within two days: breast inflammation (pain, redness, swelling).. I wish I would have been informed ahead about the substance and possible dangers.

Posted by

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Recent published research shows evidence of gadolinium remaining in the system of people, even with healthy kidneys, which is contrary to common info provided to patients saying that it's eliminated from the body in 24 hours with healthy kidney function. This research reports finding persistent gadolinium effects (hyper-intensity) in non-enhanced (no contrast) MRIs of the brain in people who had previously had gadolinium contrast, and the degree of hyper-intensity was associated with number of previous enhanced MRIs, the more gadolinium exposure, the more likely to have signs of persistent gadolinium in two areas of the brain. There is much more research that needs to be done to learn the health implications of these findings, but gadolinium is highly toxic and if it remains in the body indefinitely, this is important information for patients and doctors to know, especially when diagnosing the kinds of symptoms reported by people on this page which began soon after enhanced MRIs. To find this information, simply google 'gadolinium brain damage' or look at the March 2014 issue of the periodical, Radiology, or RSNA Radiology.

Posted by

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I have had innumerable MRIs with gadolineum due to having a brain tumor. Now I have hip impingement, scoliosis, and osteopenia. I am in pain 24/7, it never stops. I am only 56 years old.

Posted by

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I have had about 12 MRI in last 3 years to figure out what's wrong with me. Sad that the thing that was looking for What was wrong was what's been killing me. I have off charts posion of gadolinium and a small anout of lead. I have been so ill but I don't have kidney failure. So how do we that get sick with this the same way and no ones responsible ??

Posted by

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I have only had 1 MRI using Gadolinium on both hips. I have never had a more painful test in my life. Shortly afterwards, I notice both legs burning, going numb at times, I still can't sleep on my left side, the right one not so bad.I have hip pain and lower back pain so much that I can't walk upright or even stand for more that 5 minutes without leaning on some object. My bones and muscles are now starting to ache. The doctors tell me they can't see anything on the hip x-rays or back or pelvic mri. Let's just have mother nature try to heal. I've been told that there is no blood test to see if the Gadolinium is still in my system. Also, everything looks normal for my age. For someone who has been active and not had any illnesses, the fact that after an MRI with Gadolinium, I can hardly walk really stinks. No doctor wants to listen or even try to suggest an alternative treatment. Thanks for listening. Jodean

Posted by

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Is there any support group for Toxicity in Gadolinium? I just want to hear experiences and related problems with this kind of problems.

Posted by

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…………………………..Gadolinium poisoning,………………………..
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ALL SHOULD BE AWEAR Doctors and/or their corporate predecessors’ knew and recklessly disregarded the fact that their gadolinium based contrast media causes debilitating and potentially lethal side effects in patients on medication for curing of renal and/or kidney diseases failure during the time they were injected including Hepatitis C., knowingly the only medications for these is, interferon (peginterferon alfa-2a [Pegasys]) and a question also of Ribavirin, clearly knowing the FDA has reported, the patient, are to be tested for the contrast agents before the injections, and are not to have no Nuclear based contrast agents while having any nuclear test including but not limiting to MRI’s.,
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For a person to know they have renal and/or kidney diseases they had to be tested and are on Medications which are basically all the same for treatment, so everyone beware of any doctor or hospital who refuse to test you before having the injection the testing is simple they take blood from the patient and run it with the Nuclear dye where as in a day you will know if you are allergic to the Dye, if you are you can be guaranteed in getting a disablateating disease called NSF/NFD (nephrogenic systemic fibrosis or nephrogenic fibrosing dermopathy)
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Nephrogenic Systemic Fibrosis, also known as Nephrogenic Fibrosing Dermopathy, is associated with the formation of excessive scar tissue in the skin and connective tissue of other internal organs. This results in thick, coarse and hard skin, which make it difficult to move the arms, hands, legs and/or feet. Loss of the controlling of blood thinning medication, causing a person never to have an operation or they will DIE if the Gadolinium Poisoning did not kill them already from clotting moving up to the brain or lungs causing aneurysm with death to follow!
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The general public should be educated, that using Gadolinium based contrast agents, used in nuclear dye, conjunction with MIR’s and MRA’s would give 12% of the American Population NSF/NFD Disease making these same 12% allergic to Nuclear dye contrast. Giving these patients a disease, which doctors a vigorously cover up this Disease, by stating the patient condition is being caused because they are diabetic or some other disease taking the blame away from the hospital and doctors who own the machines which the nuclear dye is necessary for their negligence, where the cover up starts. Doctors refusal to test each patient to the dye, as to cost and time involved.
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Doctors are doing everything in their power to cover up this disabilitating disease, as so many people are ending up in wheelchairs and legs swollen so bad they cannot stand or walk, and stops blood thinners from working to a point that they cannot gain a control over the levels. Eventually causing death.
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Remember covering up any injury is ‘Violation of NYS (and most all other states) “laws” “Fraud”, is cover-up of injury, and hiding the information and passing it off to some other reason is called Concealment of evidence”; Yes you do have rights, also when you ask a doctor for the results of their testing and they hold them back involving weeks and months this too is concealment of evidence. Their would be no question they are manipulating the records
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Remember 42 U.S.C. § 1981 : US Code - Section 1981: Equal rights under the law
(a) Statement of equal rights All persons shall have the same right in every State and Territory to make and enforce contracts, to sue, be parties, give evidence, and to the full and equal benefit of all laws and proceedings for the security of persons and property as is enjoyed by all citizens. (b) "Make and enforce contracts” Meaning a doctor must tell you the truth not cover it up.
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42 USC § 1985 - Conspiracy to interfere with civil rights
Depriving persons of rights or privileges
If two or more persons in any State or Territory conspire or go in disguise of depriving, either directly or indirectly, any person or class of persons of the equal protection of the laws, or of equal privileges under the laws; or for the purpose of preventing or if two or more persons conspire to prevent by force, intimidation, or threat, any citizen who is lawfully entitled to giving his support in a medical or legal manner, toward or in favor of the patient or to injure any citizen in person or property on account of such support or advocacy; in any case of conspiracy, if one or more persons engaged therein do, or cause to be done, any act in furtherance of the object of such conspiracy, whereby another is injured in his person or property, or deprived of having and exercising any right or privilege of a citizen of the United States, the party so injured or deprived has an action for the recovery of damages occasioned by such injury or deprivation, against any one or more of the conspirators.
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Remember the oath all doctors took to do no harm. this is now a crime when covering up evidence or a diagnosis.
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Lead Counsel for Wave Management Corporation;

Posted by

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I begged the doctor last time I had to do a creatinine test to see if I had decent kidney function..was refused. I have had a deep headache (tis the only way to explain it), burning pain in my feet, swelling in my feet and lower legs. I have burning pain in my chest wall, pain in my spine and hips, knees and shoulders...all joints. I have had numerous MRIs with gadolinium and the first time that I noticed these symptoms was several weeks after a total body MRI. Then, I had an MRI with contrast of my thoracic and cervical spine/brain per a neurologist who then told me that the brain showed up as abnormal - it looked like sparks shooting off in my brain....when I asked her what was causing that..she said it could be a stroke, a tumor, etc. and then sent me on the road without so much as an aspirin. Since then, I have had these symptoms since the MRIs and it is very bothersome. Symptoms as above discussed. Is there a treatment that will resolve these symptoms? I need assistance ....Kate

Posted by

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hi all,i to am suffering all these symptoms described above ,i haven,t slept in 14 weeks for the pain .i live in the u.k,scotland to be precise and although i suffer from slightly high iron levels in my blood due to a genetic liver disease(g.h) i have never suffered any of these pains like i have now.It feels as though every tendon in my top half of my spine including my arm ,chest and shoulder is under strain and swollen,my groin is also sore ,all on my right side!does this sound like n.s.f to you people or am i being paranoid?can you develop it so soon after the mri?how do you diagnose it,is it by a blood test? i am going for an operation on my shoulder on the 27th of this month and i am worried this will be unbearable.Any help or advice would be greatly appreciated,thank you in advance,regards charles.p.s i am a 44 year old male.

Posted by

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The toxic truth about nano-gadolinium metal based contrast (Omniscan) most associated with it's ability to induce the lethal systemic disease, nephrogenic systemic fibrosis or NSF/NFD:

The inventor of Omniscan (Steven Quay) & colleagues tell the toxic truth in the article below.

Magnetic Resonance Imaging, Vol. 8, pp. 467-48 1, I990

Release of Gd3+ from the complex is responsible for the toxicity associated with gadoliium complexes; this release appears to be a consequence of Zn2+, Cu2+, and Ca2+ transmetallation in vivo. The added Ca2+ salt of the ligand must have a favorable toxicity so that the decrease in toxicity from in vivo transmetallation is not offset.....(GE knew it was unstable and not safe for human use,,,,yet lied and marketed it anyway).

There are many conditions claimed to predispose a patient to developing NSF after exposure to nano-gadolinium metal based contrast. But, in reality the nano-gad contrast are flawed by chemical design. All of the various nano-gad formulations must have an opening within their structure to allow the raw nano-gad metal to interact with hydrogen (water) in the patients body,,,,also allows the formulation to break down an release the highly toxic disease inducing nano-gadolinium metal (free Gd3),,their deadly flaw.
There has been a confirmed case of non-nephrogenic systemic fibrosis in a patient that had normal renal function at all gad enhanced radiological studies. It is out of Alabama and was present at the 5th Annual Symposium on NSF at Yale. It is not the only one.
Below is only the Acute Kidney Injury discussion from the 2010 ACR revision. It states that some patients have never been diagnosed with renal disease are devloping this nano-gad disease.......like myself. One exposure only to any nano-gadolinium contrast, it was a 20ml bolus dose of Omniscan. I developed NSF within weeks, it is systemic. Feet, legs, groin, abdomen, chest wall, joints and now have been diagnosed with kidney & liver disease.


American College of Radiology, contrast manual, NSF 2010 revisions: page 3,

Acute kidney injury

NSF has also developed in patients with acute kidney injury [14], even if renal function subsequently returned to normal following GBCM administration [15]. In one series, up to 20% of NSF cases were diagnosed in patients who had been in some element of TRANSIENT acute renal failure (often, BUT NOT ALWAYS, superimposed upon chronic kidney disease) at the time of GBCM administration

The co-inventor (Dr. Weinman) of the first gadolinium contrast approved for use in the USA, magnivest. public admission that "they had known there were problems with the gadolinium contrast since the 1980's".

"The train radiologist didn't see coming" http://www.diagnosticimaging.com/ismrm/2007/showArticle.jhtml?articleID=199701977

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