The journal found that the panel that had approved the medication prior to its entry into the European Union market in 2000 had concerns about potential Avandia side effects and its long-term risks, reports the Wall Street Journal.
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Once GlaxoSmithKline's second-highest selling drug, Avandia has suffered declining sales since a 2007 US study linked it to an increased risk of heart attack.
The drugmaker said that it has conducted a great deal of research into Avandia.
"We have rigorously shared our data relating to the cardiovascular safety of Avandia in a timely and transparent manner and have made extensive efforts to publish our clinical trial findings in peer review journals, at scientific meetings and via our own clinical trials website," Glaxo said.