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With enough metoclopramide aggregating in one's system, a patient faces an increased risk of the neurological disorder TD. The disorder provokes random, spasmodic movements in a patient's face, including lip smacking, puckering and rapid eye blinking, as well as movements in the arms, legs and abdomen.
Many medications have been prescribed to treat the symptoms of TD, including Zofran, Aricept and Baclofen. In smaller, more focused incidences of the condition, Botox injections can be used to subdue the involuntary spasms of the face muscles, though is not recommended for more advanced cases of the disorder, according to study author James Robert Brasic of the Johns Hopkins School of Medicine.